- Croucher Cambridge International Scholarship in 2016 at University of Cambridge
Aydan obtained his BA in Biochemistry from the University of Cambridge. His final year thesis involved working under the supervision of Dr. Darerca Owen to study the thermodynamics of the Cdc42-WASP interacting interface. After pursuing biochemical knowledge at the undergraduate level, Aydan decided to extend his interests in biochemistry and apply his skills and knowledge in the field of immunology.
Recent developments in genome sequencing and gene editing technology have allowed the application of the latter for the purpose of a large scale genetic screen. Out of the currently available gene editing technologies, CRISPR stands out by offering particularly reliable and efficient gene edition, leading to the term coined "CRISPR screen" to study biological processes.
In his PhD, Aydan will perform CRISPR screens to identify novel regulators of an immune response under the supervision of Dr. Andrew McKenzie. Such information will address our current knowledge gaps, as well as the potential to identify new therapeutic targets for immune disorders.