Joe Kwun Nam Chan 陳冠南

  • Studentship in 2021 at The University of Hong Kong

Joe Kwun Nam Chan received his Bachelor of Social Sciences degree in Psychology (1st Class Honours) from the University of Hong Kong (HKU) in 2018. He is currently a PhD student in the Department of Psychiatry of HKU under supervision of Dr. Chang Wing Chung with research interests in psychiatric epidemiology and pharmacoepidemiology. He conducts observational studies by utilizing territory-wide medical-record database to evaluate relative mortality risk of psychiatric disorders including schizophrenia and bipolar disorder due to natural and unnatural causes of death, compared to the general population. His research also compares rates of physical complications including cardiovascular diseases and renal diseases among patients with exposure to common mood stabilizers such as lithium and antipsychotics. Specifically, he develops and validates risk stratification systems using machine learning approaches to identify mood stabilizer-treated patients who are at high risk of developing physical complications and thus inform clinical decisions and to optimize management of this group of vulnerable patients.

Selected publications

Chan KN, Tong HY, Wong SM, Chen YH, Chang WC. Life expectancy and years of potential life lost in bipolar disorder: a systematic review and meta-analysis. Br J Psychiatry 2022. [Accepted]

Chan KN, Wong SM, Or CF, Chen YH, Chang WC. Risk of mortality and complications in patients with schizophrenia and diabetes mellitus: a population-based cohort study. Br J Psychiatry 2021;219: 375-382.

Chan KN, Wong SM, Yung CL, Chen YH, Chang WC. Excess mortality and life-years lost in people with bipolar disorder: an 11-year population-based cohort study. Epidemiol Psychiatr Sci 2021;30:e39. doi: 10.1017/S2045796021000305 [Online ahead of print]

Chan KN, Wong SM, Yung CL, Chen YH, Chang WC. Pre-existing chronic physical morbidity and excess mortality in people with schizophrenia: a population-based cohort study. Soc Psychiatry Psychiatr Epidemiol 2021. doi: 10.1007/s00127-021-02130-9. Online ahead of print.

Chan KN, Wong CSM, Or PF, Chen EYH, Chang WC. Diabetes complication burden and patterns and risk of mortality in people with schizophrenia and diabetes: a population-based cohort study with 16-year follow-up. Eur Neuropsychopharmacol 2021; 53: 79-88.

Chan KN, Chang WC, Ng CM, et al. Sex differences in symptom severity, cognition and psychosocial functioning among individuals with at-risk mental state for psychosis. Early Interv Psychiatry 2021. doi: 10.1111/eip.13131 [Online ahead of print]

Chang WC, Chan KN, Wong SM, Hai SH, Or CF, Chen YH. Mortality, revascularization and cardioprotective pharmacotherapy after acute coronary syndrome in patients with psychotic disorders: a population-based retrospective cohort study. Schizophr Bull 2020; 46(4): 774-784.