- University of Oxford Croucher Scholarship in 2019 at University of Oxford
Gerald Chik received his BSc degree in Chemistry from The University of Hong Kong in 2019. His early research focused on inorganic catalysis and photocatalysis. He is now pursuing a DPhil in Chemical Biology under the supervision of Professor Tom Brown at The University of Oxford. His research interest is in chemical modification of nucleotides and relevant applications on CRISPR-mediated genome editing.
His current research work highlights chemical conjugation and structural modification on CRISPR components which effect luminsecent properties and enhanced delivery efficacy into specific cells. While a high volume of researches focused on Cas protein modifications, the study of nucleotide modification in CRISPR applications remains obscure. His work aims to unravel the potential of chemically-modified gRNA, which is more amenable to chemical changes and compatible to automated synthesis, in DNA sensing and in vivo delivery protocols.