- Fellowship in 1998 at King's College London
Dr KF Lau obtained his PhD in Biochemistry at the Chinese University of Hong Kong in 1998. With the support from Croucher Foundation, he joined Professor Christopher CJ Miller’s group at Institute of Psychiatry (London, UK) in 1999. In 2007, he returned to his Alma mater as Assistant Professor at the Department of Biochemistry. He is now Associate Professor in the School of Life Sciences at the Chinese University of Hong Kong.
Dr Lau’s research focuses on the molecular and cellular pathogenesis of Alzheimer’s disease, a cureless neurodegenerative disorder. In particular, his group has been investigating the mechanisms that induce aberrant processing of Alzheimer’s disease amyloid precursor protein (APP), a pathogenic event in the disease. His group has found a number of APP interacting proteins that alter APP processing. Targeting the interactions between APP and its interactors may serve as a novel therapeutic approach for the disease.
Moreover, Dr Lau is interested in neurite development as severe neurite degeneration is a hallmark of Alzheimer’s disease. Therefore, strategies that stimulate neurite outgrowth may promote re-establishment of damaged neuro-connections. His research team has identified several molecules that promote neurite outgrowth. His work may provide essential information for the development of more effective therapeutic strategies for Alzheimer’s disease.