Chan Siu Yuen 陳小圓

  • Fellowship in 1991 at University of Cambridge
  • Scholarship in 1988 at University of Cambridge

Dr Chan obtained her BSc and MPhil from the Department of Zoology, HKU. Supported by the Croucher Scholorship, she worked under the supervision of Sir Martin Evans at the Department of Genetics, University of Cambridge, UK. The Croucher Foundation continued to support her work with a Fellowship for nearly a year at the Wellcome, CRC Institute, Cambridge, UK. She returned to Hong Kong in 1992 and took up the lectureship at the Department of Paediatrics, HKU. Since then, she is running a research Lab on Molecular Developmental Biology.


She is interested in finding how genes work and what happens when they go wrong. Her research team engineers specific changes in the mouse DNA in order to create models of human conditions. Currently the team is targeting at genes involved in brain function. The mouse models have behavioural problems similar to those in humans. These mouse models are very useful for researchers to dissect how neurodevelopment disorders, such as autism, attention deficit hyperactivity disorder and schizophrenia, develop.