Henry Lee 李慶璋

  • Fellowship in 2010 at Harvard University

Heney received a MPhil degree from the Hong Kong University of Science and Technology, where he studied the transcriptional regulation the muscle gene ColQ in Prof Karl Tsim’s laboratory. Henry then received a PhD degree from University College London under the mentorship of Prof Steve Moss, where he studied how neuronal inhibition is modulated via KCC2 intracellular trafficking. His research at the Moss laboratory was published in a series of paper (JBC 2007, MCN 2010, Nature Neurosci 2011) suggesting that mis-regulation of KCC2 leads to hyperexcitation and epilepsy. His post-doctoral research encompassed a range of topics, including critical period brain plasticity (Cell Rep 2015; Mol Pschy 2017), axon regeneration (Cell 2016), and post-traumatic epilepsy (Cerebral Cortex 2017, 2020).

Henry was honored with multiple academic awards, including a pre-doctoral fellowship from the Epilepsy Foundation, a post-doctoral fellowship from the American Heart Association, a Croucher Fellowship, and a Young Investigator Award from the American Epilepsy Society.


Henry is interested in understanding the role of neuronal inhibition and its regulation as it pertains to brain development and injury. His recent project focuses on translational research investigating a rare genetic disorder of GABA catabolism called succinic semialdehyde dehydrogenase deficiency (SSADHD). Combining expertise in molecular cloning, animal model physiology, and genetics, Henry aims to develop viable cure including gene therapy for patients with SSADHD.

Henry currently holds a dual position as a Senior Scientist at the FM Kirby Neurobiology Center and a Preclinical Scientific Program Manager at the Rosamund Stone Zander Translational Neuroscience Center at Boston Children’s Hospital, Harvard Medical School.