P C Shaw

  • Scholarship in 1983 at Imperial College London

Professor P.C. Shaw obtained his B.Sc. and then M.Phil. degree with Professor K.K. Mark at Department of Biology, The Chinese University of Hong Kong.  With a Croucher Foundation Scholarship, Professor Shaw pursued Ph.D. study with Professor Brian Hartley at the Centre for Biotechnology, Imperial College.  In 1987, he returned to Hong Kong and took up the lectureship at Department of Biochemistry, The Chinese University of Hong Kong.  He is now professor and director of Biochemistry Programme, School of Life Sciences, director of Centre for Protein Science and Crystallography and deputy director of Institute of Chinese Medicine. He has a broad interest in the ethical issues of biosciences.  He has served as chairman of the Hong Kong Bioethics Association (www.bioethics.org.hk) for two terms and now the vice-chairman.  He has also got a keen interest in philately(http://www.hkpsoc.com/COH/COH016.htm).

Currently

Professor Shaw's research focuses on the structure-function studies of proteins with pharmacological significance and the quality control of Chinese medicinal materials.  For the first area of research, his group has recently solved the protein structures of influenza H5N1 nucleoprotein, influenza B nucleoprotein and the structure of maize ribosome-inactivating protein. His group is now employing a battery of biochemical and biophysical techniques to characterize selected influenza proteins and their interacting partners and screen for chemicals to inhibit the virus.  For the second area of research, Professor Shaw has pioneered in the molecular authentication of Chinese medicinal materials.  His group has constructed the first medicinal materials DNA barcode database, which contains more than 30,000 DNA sequences and 1600 types of medicinal materials.  He has published 170 refereed articles, two books and has obtained two US and two Chinese patents.