Pui-Chuen "Wallace" Hui

  • Fellowship in 2014 at Harvard University

Pui-Chuen “Wallace” Hui is a postdoctoral fellow at Prof. Brett Bouma's lab in Wellman Center for Photomedicine at Massachusetts General Hospital, working on novel imaging strategies in biomedical imaging particularly in the context of optical coherence tomography. Dr. Hui's graduate work was performed in the Laboratory of Nanoscale Optics of Prof. Marko Loncar in the School of Engineering and Applied Sciences at Harvard University, where his research focus was on the detection and optomechanical counteraction of the Casimir effect in an integrated MOEMS platform. Mr. Hui received an SM in Engineering Science from Harvard University in 2012. He obtained his BS in Applied and Engineering Physics from Cornell University in 2008, where he worked with Prof. Farhan Rana on terahertz biomolecule detection and Prof. Alex Gaeta on nonlinear optics.

A typical morning for Wallace starts with a quiet time in the Scriptures, which prepares him for the energy needed in everyday research and occasional algebraic breakthrough in his calculations.  Wallace is also a classical music aficionado, and used to be an avid performer of choral music.  A proud alumnus of both the Cornell Glee Club (07-08) and Harvard Glee Club (08-10).


1. Novel strategies for imaging

Constructions of cost-effective sensing kernels for generalized-domain optical coherence tomography which utilizes imaging light sources and detectors of low-cost while maintaining high detection sensitivity.

2. Neuronal imaging

Systematic investigations of optical response during neuronal activities using optical coherence tomography guided by genetically expressed voltage-sensitive fluorescent indicators.

3. Integration of microfabricated devices on OCT probes


  • Rodriguez, A. W., Hui, P.-C., Woolf, D. P., Johnson, S. G., Lončar, M. and Capasso, F. (2015), Classical and fluctuation-induced electromagnetic interactions in micron-scale systems: designer bonding, antibonding, and Casimir forces. Ann. Phys., 527: 45–80. doi: 10.1002/andp.201400160
  • P. Hui, D. Woolf, E. Iwase, Y. Sohn, D. Ramos, M. Khan, A. W. Rodriguez, S. G. Johnson, F. Capasso, M. Lončar “Optical bistability with a repulsive optical force in coupled silicon photonic crystal membranes” Applied Physics Letters, 103 021102 (2013)
  • D.N. Woolf, P.C. Hui, E. Iwase, M. Khan, A.W. Rodriguez, P.B. Deotare, I. Bulu, S.G. Johnson, F. Capasso, and M. Lončar “Optomechanical and Photothermal Interactions in Suspended Photonic Crystal Membranes” Optics Express (accepted) 2013; arXiv:1210.8023(2013)
  • E. Iwase, P.C. Hui, D. Woolf, A.W. Rodriguez, S.G. Johnson, F. Capasso, and M. Lončar, "Control of buckling in large micromembranes using engineered support structures," J. Michromech. Mircoeng., Vol. 22 065028 (2012)
  • A.W. Rodriguez, D. Woolf, P.C. Hui, E. Iwase, A.P. McCauley, F. Capasso, M. Lončar, S.G. Johnson, "Designing evanescent optical interactions to control the expression of Casimir forces in optomechanical structures", APL, Vol. 98, 194105 (2011)
  • A.W. Rodriguez, A.P. McCauley, P.C. Hui, E. Iwase, F. Capasso, M Lončar, and S.G. Johnson, "Bonding, antibonding and tunable optical forces in asymmetric membranes", Optics Express, Vol. 19,2225-2241 (2011)
  • B. Shim, S. E. Schrauth, C. J. Hensley, L. T. Vuong, P. Hui, A. A. Ishaaya, and A. L. Gaeta, “Controlled Interactions of Femtosecond Light Filaments in Air,” Phys. Rev. A 81,061803(R) (2010)
  • P. A. George, W. Hui, F. Rana, B. G. Hawkins, A. E. Smith, B. J. Kirby, “Microfluidic Devices for Terahertz Spectroscopy of Biomolecules,” Optics Express, vol. 16, 1577 (2008).
Invited talks: 
1. Eiji Iwase, Pui-Chuen Hui, David Woolf, Alejandro W. Rodriguez, Mughees Khan, Steven G. Johnson, Federico Capasso, Marko Loncar, "Towards optical manipulation of Casimir force using free-standing membranes with engineered optical and mechanical properties", (invited talk) CLEO/QELS: 2012, San Jose, CA, May 6-11,2012

2. David Woolf; Pui-Chuen Hui; Eiji Iwase; Alejandro Rodriguez; Alexander McCauley; Igor Lovchinsky; Mughees Khan; Steven Johnson; Marko Loncar; Federico Capasso, "Optical Bonding And Antibonding Forces In Asymmetric Geometries For Casimir Force Detection", (invited talk) CLEO/QELS: 2011, Baltimore, MD, May 4, 2011

1. P. Hui, A. Rodriguez, D. Woolf, E. Iwase, M. Khan, F. Capasso, and M. Loncar, "Strong Mechanical Nonlinearity of Optomechanically Driven Suspended Photonic Crystal Membrane," in CLEO: 2015, OSA Technical Digest (online) (Optical Society of America, 2015), paper STh4I.3.

2. Pui-Chuen Hui; David Woolf; Eiji Iwase; Irfan Bulu; Alejandro Rodriguez; Mughees Khan; Parag Deotare; Steven Johnson; Federico Capasso; Marko Loncar, "Dynamics of a tethered silicon photonic crystal membrane due to optical gradient, photothermal and Casimir forces," CLEO/QELS: 2012, San Jose, CA, May 6-11,2012

3. D. Woolf, P. C. Hui, A. W. Rodriguez, E. Iwase, M. Khan, R. Ng, S. G. Johnson, F. Capasso, and M. Loncar, “Cavity optomechanics and the Casimir force: dynamics and applications”, SPIE Photonics West, San Francisco, California, USA, February 2-7, 2013